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ExcretionPara asegurarse que tadalafil es seguro para usted, dígale a su médico acerca de sus otras condiciones médicas, especialmente. Patent 8,841,446

Initial dose: 50 mg orally once a day, as needed, 1 hour prior to sexual activity where to order cialis Sildenafil belongs to a class of medications called phosphodiesterase inhibitors, which work by increasing blood flow to the penis during sexual activity, resulting in an erection. Viagra (sildenafil) is used for the treatment of erectile dysfunction. Viagra works by inhibiting the chemical phosphodiesterase, which leads to an increase in the effect of nitric oxide. Nitric oxide allows the smooth muscles inside the penis to relax, promoting more blood flow to the area during sexual arousal or stimulation. Viagra begins to work within about an hour and the effects can last for up to four hours. In clinical studies, Viagra was given to more than 3,000 patients aged 19 to 87 years with erectile dysfunction of different causes. Viagra is rapidly absorbed after oral administration, with a mean absolute bioavailability of 41% (range 25–63%). The pharmacokinetics of sildenafil are dose-proportional over the recommended dose range. It is eliminated predominantly by hepatic metabolism (mainly CYP3A4) and is converted to an active metabolite with properties similar to the parent, sildenafil. Both sildenafil and the metabolite have terminal half lives of about 4 hours.

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Moderate (CrCl 30-50 mL/min): Not to exceed 5 mg PO once daily initially; maximum dosage, 10 mg PO q48hrLEVITRA can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke.

Take Viagra exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. brand viagra Contraindications

In vitro studies have shown that vardenafil is a selective inhibitor of PDE5. The inhibitory effect of vardenafil is more selective on PDE5 than for other known phosphodiesterases (>15-fold relative to PDE6, >130-fold relative to PDE1, >300-fold relative to PDE11, and >1,000-fold relative to PDE2, 3, 4, 7, 8, 9, and 10).Overdose

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